In vitro anti-Salmonella activity of extracts from selected Kenyan medicinal plants

Abstract

The aim of this study was to determine in vitro anti-Salmonella activity of extracts of five selected Kenyan medicinal plants against Salmonella ser. Typhi and Salmonella ser. Typhimurium. The extracts from Tithonia diversifolia, Warburgia ugandesis, Croton megalocarpus, Carissa edulis and Launae cornuta plants traditionally used in treatment of typhoid fever were screened for anti-Salmonella activity using disc diffusion and microdilution techniques. The results from the present study have shown that out of thirty six extracts investigated, only nine extracts from T. diversifolia and W. ugendensis showed activity against Salmonella ser. Typhi and Salmonella ser. Typhimurium at 1000 mg/ml. The inhibition zone of ethyl acetate, hexane and methanol extracts of T. diversifolia leaves, ethyl acetate and hexane extracts of T. diversifolia flowers, ethyl acetate and hexane extracts of W. ugandensis stem barks, ethyl acetate …