Jung-Su Chang; Chyi-Huey Bai; Zu-Chieh Huang; Eddy Owaga; Kuo-Ching Chao; Chun-Chao Chang; Hung-Yi Chiou
Abstract:
Interleukin 10 (lL-10) has multifaceted anti-inflammatory properties that are known to regulate insulin sensitivity and atherosclerotic development. However, studies in children are limited and have yielded
Conflicting results. The aim of this study was to evaluate whether changes in this circulating anti-inflammatory
cytokine is a marker for metabolic syndrome.
Materials and methods This cross-sectional study involved children and young adolescents from eight elementary schools and two junior high schools located in Taipei end New Taipei City. A total of 553 children ages
8, 11 and 13 years old were included in the analysis. Parameters for obesity, anti- and pro-inflammatory
cytokines, and metabolic risk profiles were evaluated.